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Product Information:

SLM6031434 HCl

SLM6031434 hydrochloride is a highly selective sphingosine kinase 2 (SphK2) inhibitor with Kis of 0.4 μM, 0.5 μM, >20 μM, 22 μM for mSphK2, rSphK2, mSphK1 and rSphK1, respectively. SLM6031434 hydrochloride decrease Sphingosine 1-phosphate (S1P) levels in U937 monocytic leukemia cells. SLM6031434 hydrochloride has the potential for renal fibrosis research[1][2].

Cat. No.: EX-A15330    Purity: >98%
Chemical
Chemical structure of SLM6031434 HCl


For research only, Do not use for Human!

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SynonymsSLM6031434 hydrochloride
CAS No.1897379-34-8
Purity>98%
FormulaC22H31ClF3N5O2
Mol Weight489.962
 
 
Reference:  

[1]. Yugesh Kharel, et al. Sphingosine Kinase 2 Inhibition and Blood Sphingosine 1-Phosphate Levels. J Pharmacol Exp Ther. 2015 Oct;355(1):23-31.

CoACoA of SLM6031434 HCl
Smiles:CCCCCCCCOC1=C(C=C(C=C1)C2=NOC(=N2)[C@@H]3CCCN3C(=N)N)C(F)(F)F.Cl

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